Achillinin A, a cytotoxic guaianolide from the flower of Yarrow, Achillea millefolium.
نویسندگان
چکیده
Achillinin A (2β,3β-epoxy-1α,4β,10α-trihydroxyguai-11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LC-kj and QG-90 cells with 50% inhibitory concentration (IC(50)) values of 5.8, 10 and 0.31 µM, respectively.
منابع مشابه
Terpenoids from Achillea setacea.
The aerial parts of Achillea setacea afforded, in addition of a rare monoterpene triol and 12 known sesquiterpene lactones, a new guaianolide containing an endoperoxide ring. Its structure was elucidated by spectral methods.
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عنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 75 8 شماره
صفحات -
تاریخ انتشار 2011